Knowledge Discovery in RNA Sequence Families of HIV
نویسندگان
چکیده
Secondary structure prediction is a standard tool in the analysis of RNA sequences. The prediction of RNA secondary structures is inherently non-local. This makes the analysis of long sequences (more than 4000 nucleotides) infeasible on present-day workstations. An implementation of the secondary structure prediction algorithm for hypercube-type parallel computers allows to compute eeciently the structure of complete RNA virus genomes such as HIV-1 and other lentiviruses.
منابع مشابه
Knowledge Discovery in RNA Sequence Families of HIV Using Scalable Computers
The prediction of RNA secondary structure on the basis of sequence information is an important tool in biosequence analysis. However, it has typically been restricted to molecules containing no more than 4000 nucleotides due to the computational complexity of the underlying dynamic programming algorithm used. We desribe here an approach to RNA sequence analysis based upon scalable computers, wh...
متن کاملSet up of Genotyping Test for Detection of HIV-1 Drug Resistance
Background and Aims: Genotyping assay has been accepted as a guidance in the therapeutic management of Human Immunodeficiency virus 1 (HIV-1). But, it is not commonly used in our country due to its high running cost. The aim of this study is evaluate an in-house genotyping resistance test (GRT) for HIV-1. Methods: HIV-1 RNA of 20 samples were extracted from plasma and RT Nested- PCR was perform...
متن کاملThe Knowledge, Attitude and Behavior of HIV/AIDS Patients’ Family toward Their Patients before and after Counseling
Background: Acquired immunodeficiency may impose considerable consequences on patients’ family behaviors toward them. The objective of the present study was to investigate whether a counseling program atBehavioralCounselingCenter in the city ofShiraz,Iran could change the attitude, knowledge and behavior of patients' family members. Methods: 125 HIV/AIDS patients’ family members were interviewe...
متن کامل3D RNA and Functional Interactions from Evolutionary Couplings
Non-coding RNAs are ubiquitous, but the discovery of new RNA gene sequences far outpaces the research on the structure and functional interactions of these RNA gene sequences. We mine the evolutionary sequence record to derive precise information about the function and structure of RNAs and RNA-protein complexes. As in protein structure prediction, we use maximum entropy global probability mode...
متن کاملP-215: Discovery of A Novel APA Variant of A Human Potential Gene Based on Expressed Sequenced Tags Analysis
Background: Expressed sequence tags (ESTs) are sequences of cDNA fragments prepared from different tissue sources. There are over one million of these sequences in the publicly available database, and these sequences are believed to represent more than half of all human genes. The ESTs belong to different cDNA libraries, was prepared from one particular cell type, organ, or tumor. Therefore, th...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 1996